Questiomycin B

Questiomycin B

SCHEMBL8006530

Nc1cc2ccccc2cc1C(=O)O.Nc1ccccc1O

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.79
ALOX15 P16050 2/20 0.52
TSHR P16473 1/20 0.52
GRIN2D O15399 1/20 0.49
GRIN2A Q12879 1/20 0.49
GRIN2B Q13224 1/20 0.49
GRIN2C Q14957 1/20 0.49
KDM4E B2RXH2 4/20 0.47
ALDH1A1 P00352 3/20 0.47
HPGD P15428 3/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
HMGB1 P09429 1/20 0.47
CA4 P22748 1/20 0.47
CA6 P23280 1/20 0.47
CA7 P43166 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
CA9 Q16790 1/20 0.47
NAPRT Q6XQN6 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29475880 0.89 IDO1 (1.00) IDO1ALOX15TSHRKDM4EALDH1A1
SCHEMBL197490 0.89 IDO1 (1.00) IDO1ALOX15TSHRKDM4EALDH1A1
SCHEMBL8006518 0.89 IDO1 (1.00) IDO1ALOX15TSHRKDM4EALDH1A1
SCHEMBL7996107 0.86 IDO1 (0.68) IDO1TSHRGRIN2DGRIN2AGRIN2B
SCHEMBL8003432 0.81 IDO1 (0.70) IDO1GRIN2DGRIN2AGRIN2BGRIN2C
SCHEMBL7592067 0.80 IDO1 (0.74) IDO1ALOX15KDM4EALDH1A1HPGD
Anthranilic Acid SCHEMBL6430889 0.80 ALOX15 (0.62) IDO1ALOX15TSHRKDM4EALDH1A1
SCHEMBL10796264 0.79 GRIN2D (0.67) IDO1ALOX15GRIN2DGRIN2AGRIN2B
3-Aminophenol SCHEMBL7991041 0.79 IDO1 (0.72) IDO1ALOX15GRIN2DGRIN2AGRIN2B
SCHEMBL8003575 0.79 IDO1 (0.66) IDO1TSHRGRIN2DGRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6117996-A COMPLEXING; SEPARATION; PURIFICATION OF PROTEINS NOVO NORDISK A/S (DK) 2000-09-12 US disclosed
US-4086223-A Asymmetrical 1:2-chromium complex azo dyestuffs CIBA-GEIGY AG (CH) 1978-04-25 US disclosed