SCHEMBL7991046 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	MMP1	P03956	5/20	0.39

▸	MMP2	P08253	5/20	0.39

▸	MMP3	P08254	4/20	0.39

▸	RAB9A	P51151	1/20	0.36

▸	TSHR	P16473	3/20	0.36

▸	MAPT	P10636	1/20	0.35

▸	ALDH1A1	P00352	1/20	0.35

▸	PDF	Q9HBH1	1/20	0.33

▸	MMP9	P14780	1/20	0.33

▸	MMP8	P22894	1/20	0.33

▸	CASR	P41180	1/20	0.33

▸	NPSR1	Q6W5P4	1/20	0.33

▸	MEN1	O00255	1/20	0.32

▸	KMT2A	Q03164	1/20	0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7991042	1.00	MMP1 (0.39)	MMP1MMP2MMP3RAB9ATSHR
SCHEMBL7976481	0.86	RAB9A (0.42)	RAB9ATSHRMAPTALDH1A1CASR
SCHEMBL7976479	0.86	RAB9A (0.42)	RAB9ATSHRMAPTALDH1A1CASR
SCHEMBL7989849	0.80	PDF (0.37)	MMP1MMP2MMP3PDFMMP9
SCHEMBL7976169	0.77	PDF (0.44)	MMP1MMP2MMP3PDFMMP9
SCHEMBL7977102	0.77	PDF (0.44)	MMP1MMP2MMP3PDFMMP9
SCHEMBL7992880	0.77	PDF (0.40)	MMP1MMP2MMP3PDFMMP9
SCHEMBL7990517	0.75	RAB9A (0.43)	RAB9ATSHRMAPTALDH1A1CASR
SCHEMBL7990520	0.75	RAB9A (0.43)	RAB9ATSHRMAPTALDH1A1CASR
SCHEMBL7995047	0.74	PDF (0.43)	MMP1MMP2MMP3PDFMMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2001040198-A2	MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS	AVENTIS PHARMA S.A. (FR)	2001-06-07	—	—	WO	disclosed