Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991183 | 0.86 | KDM4E (0.49) | KDM4EHPGDKMT2AHSD17B10GLA | |
| SCHEMBL7988142 | 0.85 | KDM4E (0.53) | KDM4EHPGDKMT2AHSD17B10GLA | |
| SCHEMBL7991327 | 0.84 | KDM4E (0.52) | KDM4EHPGDKMT2AHSD17B10GLA | |
| SCHEMBL7991051 | 0.83 | KDM4E (0.50) | KDM4EHPGDKMT2AHSD17B10GLA | |
| SCHEMBL7989163 | 0.82 | PTPN11 (0.48) | SMPD1THRATHRBMAPK1 | |
| SCHEMBL7991229 | 0.82 | KDM4E (0.49) | KDM4EHPGDKMT2AHSD17B10GLA | |
| SCHEMBL7991331 | 0.81 | KDM4E (0.53) | KDM4EHPGDKMT2AHSD17B10GLA | |
| SCHEMBL7977331 | 0.80 | KDM4E (0.49) | KDM4EHPGDKMT2AHSD17B10GLA | |
| SCHEMBL7992415 | 0.79 | KDM4E (0.51) | KDM4EHPGDKMT2AHSD17B10GLA | |
| SCHEMBL7987500 | 0.79 | SMPD1 (0.53) | KDM4EHPGDKMT2AHSD17B10GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055117-A1 | NOVEL ISOQUINOLINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2001-08-02 | — | — | WO | disclosed |