Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991453 | 0.86 | KDM4E (0.51) | KDM4EHPGDKMT2AHSD17B10GLA | |
| SCHEMBL7988142 | 0.84 | KDM4E (0.53) | KDM4EHPGDKMT2AHSD17B10GLA | |
| SCHEMBL7991051 | 0.83 | KDM4E (0.50) | KDM4EHPGDKMT2AHSD17B10GLA | |
| SCHEMBL7991327 | 0.83 | KDM4E (0.52) | KDM4EHPGDKMT2AHSD17B10GLA | |
| SCHEMBL7995609 | 0.83 | S1PR1 (0.40) | KDM4EGAAMAOAMAPK1LMNA | |
| SCHEMBL7991229 | 0.80 | KDM4E (0.49) | KDM4EHPGDKMT2AHSD17B10GLA | |
| SCHEMBL7991331 | 0.79 | KDM4E (0.53) | KDM4EHPGDKMT2AHSD17B10GLA | |
| SCHEMBL7977331 | 0.78 | KDM4E (0.49) | KDM4EHPGDKMT2AHSD17B10GLA | |
| SCHEMBL7994703 | 0.78 | KDM4E (0.45) | KDM4EHPGDKMT2AHSD17B10GLA | |
| SCHEMBL7992415 | 0.78 | KDM4E (0.51) | KDM4EHPGDKMT2AHSD17B10GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055117-A1 | NOVEL ISOQUINOLINE DERIVATIVES, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2001-08-02 | — | — | WO | disclosed |