Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.58 |
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | MAOA | P21397 | 3/20 | 0.58 |
| ▸ | TOP1 | P11387 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.49 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.49 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.49 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PLEC | Q15149 | 1/20 | 0.49 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11525810 | 0.88 | EGFR (0.60) | KMT2AMAPTMEN1MAOATOP1 | |
| SCHEMBL8612875 | 0.86 | MAPT (0.63) | KMT2AMAPTMEN1MAOASMN1; SMN2 | |
| SCHEMBL13183079 | 0.81 | MAPT (0.61) | KMT2AMAPTMEN1MAOASMN1; SMN2 | |
| SCHEMBL11524597 | 0.81 | TOP1 (0.66) | KMT2AMAPTMEN1TOP1SMN1; SMN2 | |
| SCHEMBL6367155 | 0.81 | TOP1 (0.69) | KMT2AMAPTMEN1TOP1SMN1; SMN2 | |
| SCHEMBL13159617 | 0.81 | MEN1 (0.56) | KMT2AMAPTMEN1MAOASMN1; SMN2 | |
| SCHEMBL11015465 | 0.80 | KMT2A (0.51) | KMT2AMAPTMEN1TOP1SMN1; SMN2 | |
| SCHEMBL17460658 | 0.78 | MEN1 (0.56) | KMT2AMAPTMEN1MAOASMN1; SMN2 | |
| SCHEMBL11529372 | 0.77 | EGFR (0.57) | KMT2AMAPTMEN1TOP1SMN1; SMN2 | |
| SCHEMBL12581680 | 0.77 | TTR (0.44) | KMT2AMAPTMEN1MAOATOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001092215-A2 | SUPEROXIDE-GENERATING DIAZENIUMDIOLATES, COMPOSITIONS COMPRISING SAME, AND METHODS FOR USING SAME | US HEALTH (US) | 2001-12-06 | — | — | WO | disclosed |