SCHEMBL8612875

SCHEMBL8612875

O=C(O)Oc1ccc(O)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.63
MEN1 O00255 9/20 0.63
KMT2A Q03164 9/20 0.63
MAOA P21397 5/20 0.63
TDP1 Q9NUW8 5/20 0.53
MCL1 Q07820 5/20 0.53
POLB P06746 4/20 0.53
HPGD P15428 4/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
PABPC1 P11940 1/20 0.53
CSNK1A1 P48729 1/20 0.53
CSNK1D P48730 1/20 0.53
BLM P54132 1/20 0.53
PLEC Q15149 1/20 0.53
CSNK1G1 Q9HCP0 1/20 0.53
ALDH1A1 P00352 8/20 0.49
KDM4E B2RXH2 4/20 0.49
USP2 O75604 2/20 0.49
DUSP3 P51452 1/20 0.49
APEX1 P27695 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5306728 0.91 MAPT (0.57) MAPTMEN1KMT2AMAOATDP1
SCHEMBL5309173 0.88 PIM1 (0.47) MAPTMEN1KMT2AMAOATDP1
SCHEMBL7991657 0.86 KMT2A (0.58) MAPTMEN1KMT2AMAOATDP1
SCHEMBL13183079 0.85 MAPT (0.61) MAPTMEN1KMT2AMAOATDP1
SCHEMBL5311970 0.85 EGFR (0.67) MAPTMEN1KMT2AMAOATDP1
SCHEMBL13159617 0.84 MEN1 (0.56) MAPTMEN1KMT2AMAOATDP1
SCHEMBL11131456 0.82 MEN1 (0.64) MAPTMEN1KMT2AMAOATDP1
SCHEMBL17460658 0.81 MEN1 (0.56) MAPTMEN1KMT2AMAOATDP1
SCHEMBL5305929 0.81 MAPT (0.60) MAPTMEN1KMT2AMAOATDP1
SCHEMBL10772648 0.80 MAPT (0.63) MAPTMEN1KMT2AMAOATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024048429-A1 COSMETIC PROCESS USING PARTICLE WITH MICROPROTRUSION L'OREAL (FR) 2024-03-07 WO disclosed
WO-2023228870-A1 COMPOSITION FOR COLORING KERATIN FIBERS L'OREAL (FR) 2023-11-30 WO disclosed
US-11672743-B2 Composition for keratin fibers comprising a direct dye L'OREAL (FR) 2023-06-13 US disclosed
US-20230051189-A1 COSMETIC PROCESS USING MICRONEEDLE SHEET L'OREAL (FR) 2023-02-16 US disclosed
US-11540992-B2 Process and composition for coloring keratin fibers L'OREAL (FR) 2023-01-03 US disclosed
EP-3886795-B1 COMPOSITION FOR KERATIN FIBERS COMPRISING A DIRECT DYE OREAL (FR) 2022-12-14 EP disclosed
US-20220015997-A1 COMPOSITION FOR KERATIN FIBERS COMPRISING A DIRECT DYE L'OREAL (FR) 2022-01-20 US disclosed
US-20210369581-A1 PROCESS AND COMPOSITION FOR COLORING KERATIN FIBERS L'OREAL (FR) 2021-12-02 US disclosed
EP-3886795-A1 COMPOSITION FOR KERATIN FIBERS COMPRISING A DIRECT DYE L'OREAL (FR) 2021-10-06 EP disclosed
EP-3843696-A1 PROCESS AND COMPOSITION FOR COLORING KERATIN FIBERS L'OREAL (FR) 2021-07-07 EP disclosed
WO-2017094865-A1 COMPOSITION FOR DYEING KERATIN FIBERS L'OREAL (FR) 2017-06-08 WO disclosed
WO-2017094866-A1 COMPOSITION FOR DYEING KERATIN FIBERS L'OREAL (FR) 2017-06-08 WO disclosed
EP-3164108-A1 COMPOSITION FOR DYEING KERATIN FIBERS L'OREAL (FR) 2017-05-10 EP disclosed
CN-106456486-A Composition for dyeing keratin fibers 莱雅公司 2017-02-22 CN disclosed
WO-2016084972-A1 OIL-RICH COMPOSITION L'OREAL (FR) 2016-06-02 WO disclosed
WO-2016084971-A1 SILICONE OIL-RICH COMPOSITION L'OREAL (FR) 2016-06-02 WO disclosed
WO-2015198923-A1 COMPOSITION FOR KERATIN FIBERS L'OREAL (FR) 2015-12-30 WO disclosed
WO-2015186813-A1 COMPOSITION FOR DYEING KERATIN FIBERS L'OREAL (FR) 2015-12-10 WO disclosed
WO-2013125053-A1 PROCESS FOR TREATING KERATIN FIBERS L'OREAL (FR) 2013-08-29 WO disclosed
US-5725603-A Process for the direct dying of keratinous fibres using natural dyes and water vapor L'OREAL (FR) 1998-03-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210369581-A1 PROCESS AND COMPOSITION FOR COLORING KERATIN FIBERS KRT18, PRKDC, KIF5C MAPT 1335/4885MEN1 4246/4885KMT2A 1022/4885
US-11540992-B2 Process and composition for coloring keratin fibers KRT18, PRKDC, KIF5C MAPT 1335/4885MEN1 4246/4885KMT2A 1022/4885
US-20220015997-A1 COMPOSITION FOR KERATIN FIBERS COMPRISING A DIRECT DYE KRT18, MKI67, DSG1 MAPT 678/4885MEN1 3316/4885KMT2A 758/4885
US-11672743-B2 Composition for keratin fibers comprising a direct dye KRT18, MKI67, DSG1 MAPT 678/4885MEN1 3316/4885KMT2A 758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.