Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.48 |
| ▸ | CES1 | P23141 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18017521 | 1.00 | CES2 (0.48) | CES2CES1ALDH1A1MAPTGAA | |
| SCHEMBL7991679 | 1.00 | CES2 (0.48) | CES2CES1ALDH1A1MAPTGAA | |
| SCHEMBL13604742 | 0.87 | HTT (0.55) | CES2CES1ALDH1A1MAPTGAA | |
| SCHEMBL7991894 | 0.87 | MAPT (0.53) | CES2CES1ALDH1A1MAPTGAA | |
| SCHEMBL4372776 | 0.87 | HTT (0.55) | CES2CES1ALDH1A1MAPTGAA | |
| SCHEMBL4372774 | 0.87 | HTT (0.55) | CES2CES1ALDH1A1MAPTGAA | |
| SCHEMBL7991893 | 0.87 | MAPT (0.53) | CES2CES1ALDH1A1MAPTGAA | |
| SCHEMBL7978018 | 0.87 | MAPT (0.49) | CES2CES1ALDH1A1MAPTGAA | |
| SCHEMBL7978024 | 0.87 | MAPT (0.49) | CES2CES1ALDH1A1MAPTGAA | |
| SCHEMBL19663921 | 0.87 | ALDH1A1 (0.61) | CES2CES1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |