Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.47 |
| ▸ | CES1 | P23141 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991894 | 1.00 | MAPT (0.53) | MAPTSMN1; SMN2CES2CES1ALDH1A1 | |
| SCHEMBL7991675 | 0.87 | CES2 (0.48) | MAPTSMN1; SMN2CES2CES1ALDH1A1 | |
| SCHEMBL7991679 | 0.87 | CES2 (0.48) | MAPTSMN1; SMN2CES2CES1ALDH1A1 | |
| SCHEMBL18017521 | 0.87 | CES2 (0.48) | MAPTSMN1; SMN2CES2CES1ALDH1A1 | |
| SCHEMBL7978018 | 0.84 | MAPT (0.49) | MAPTSMN1; SMN2CES2CES1ALDH1A1 | |
| SCHEMBL4372774 | 0.84 | HTT (0.55) | MAPTCES2CES1ALDH1A1GAA | |
| SCHEMBL13604742 | 0.84 | HTT (0.55) | MAPTCES2CES1ALDH1A1GAA | |
| SCHEMBL4372776 | 0.84 | HTT (0.55) | MAPTCES2CES1ALDH1A1GAA | |
| SCHEMBL7978024 | 0.84 | MAPT (0.49) | MAPTSMN1; SMN2CES2CES1ALDH1A1 | |
| SCHEMBL1968821 | 0.84 | ALDH1A1 (0.61) | MAPTSMN1; SMN2CES2CES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |