Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 1/20 | 0.44 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.39 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.34 |
| ▸ | F2R | P25116 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.32 |
| ▸ | CCR9 | P51686 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7985465 | 0.99 | ABCC8 (0.43) | ABCC8KCNJ11NR1H4MAP3K5NR1I2 | |
| SCHEMBL7988035 | 0.87 | SMN1; SMN2 (0.39) | HPGDSMN1; SMN2ALDH1A1TP53YTHDC1 | |
| SCHEMBL7984468 | 0.87 | ABCC8 (0.46) | ABCC8KCNJ11NR1H4NR1I2EGLN3 | |
| SCHEMBL7985513 | 0.86 | MET (0.43) | HPGDSMN1; SMN2ALDH1A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7988141 | 0.86 | SMN1; SMN2 (0.39) | HPGDSMN1; SMN2ALDH1A1TP53YTHDC1 | |
| SCHEMBL7984746 | 0.86 | ABCC8 (0.46) | ABCC8KCNJ11NR1H4NR1I2EGLN3 | |
| SCHEMBL7984365 | 0.86 | HPGD (0.45) | HPGDSMN1; SMN2ALDH1A1YTHDC1CYP11B1 | |
| Hydrochloric Acid SCHEMBL7988731 | 0.85 | MET (0.42) | HPGDSMN1; SMN2ALDH1A1CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL7992066 | 0.85 | HPGD (0.44) | HPGDSMN1; SMN2ALDH1A1YTHDC1CYP11B1 | |
| SCHEMBL7985639 | 0.84 | ABCC8 (0.44) | ABCC8KCNJ11NR1H4NR1I2EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |