Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.35 |
| ▸ | YTHDC1 | Q96MU7 | 2/20 | 0.33 |
| ▸ | MET | P08581 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7988141 | 0.99 | SMN1; SMN2 (0.39) | SMN1; SMN2LMNACYP11B1CYP11B2HTT | |
| SCHEMBL7985513 | 0.89 | MET (0.43) | SMN1; SMN2CYP11B1CYP11B2HTTCTSL | |
| SCHEMBL7984365 | 0.89 | HPGD (0.45) | SMN1; SMN2CYP11B1CYP11B2CTSLHPGD | |
| Hydrochloric Acid SCHEMBL7988731 | 0.88 | MET (0.42) | SMN1; SMN2CYP11B1CYP11B2HTTCTSL | |
| Hydrochloric Acid SCHEMBL7992066 | 0.88 | HPGD (0.44) | SMN1; SMN2CYP11B1CYP11B2CTSLHPGD | |
| SCHEMBL7991685 | 0.87 | ABCC8 (0.44) | SMN1; SMN2CYP11B1CYP11B2HPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL7985465 | 0.86 | ABCC8 (0.43) | SMN1; SMN2CYP11B1CYP11B2HPGDALDH1A1 | |
| SCHEMBL7988356 | 0.86 | ALDH1A1 (0.44) | SMN1; SMN2LMNACYP11B1CYP11B2HTT | |
| SCHEMBL7987434 | 0.86 | CYP11B1 (0.42) | SMN1; SMN2LMNACYP11B1CYP11B2HTT | |
| SCHEMBL7989377 | 0.85 | LMNA (0.44) | SMN1; SMN2LMNACYP11B1CYP11B2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |