Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7996733 | 0.83 | MMP3 (0.49) | MMP3MAPTKMT2AMEN1NPC1 | |
| SCHEMBL7487118 | 0.80 | MMP3 (0.65) | MMP3MAPTKMT2AMEN1NPC1 | |
| SCHEMBL17509445 | 0.74 | CYP3A4 (0.49) | MAPTKMT2AMEN1SMN1; SMN2HPGD | |
| SCHEMBL12904279 | 0.73 | CYP3A4 (0.48) | KMT2AHPGDCASP1CYP3A4 | |
| SCHEMBL11646131 | 0.73 | MAPT (0.62) | MAPTKMT2AMEN1NPC1RAB9A | |
| SCHEMBL8100905 | 0.70 | CYP3A4 (0.61) | KMT2ANPC1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL7071011 | 0.70 | CYP3A4 (0.53) | HPGDCYP3A4 | |
| SCHEMBL17509421 | 0.70 | NCEH1 (0.58) | MMP3SMN1; SMN2HPGDCTSD | |
| SCHEMBL4956920 | 0.69 | HPGD (0.56) | RAB9AHPGDCASP1CTSD | |
| SCHEMBL7990117 | 0.69 | MMP3 (0.61) | MMP3KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288261-B1 | DRUGS FOR INHIBITION OF ENZYMES | ABBOTT LABORATORIES | 2001-09-11 | — | — | US | disclosed |