Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MGAM | O43451 | 1/20 | 0.50 |
| ▸ | SI | P14410 | 1/20 | 0.50 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CIT | O14578 | 1/20 | 0.46 |
| ▸ | GAK | O14976 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7988409 | 0.91 | ALOX5 (0.50) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7991953 | 0.91 | RAB9A (0.52) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7990080 | 0.89 | MEN1 (0.53) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7977513 | 0.89 | MEN1 (0.54) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7977577 | 0.89 | RAB9A (0.47) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7991917 | 0.89 | MEN1 (0.47) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7977987 | 0.88 | ALOX5 (0.48) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7991779 | 0.88 | AURKA (0.49) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7991856 | 0.87 | LMNA (0.55) | MEN1KMT2AALDH1A1MAPTRAB9A | |
| SCHEMBL7989929 | 0.87 | MAPT (0.58) | MEN1KMT2AALDH1A1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |