Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991843 | 0.88 | AURKA (0.45) | DGAT1USP2ALDH1A1HPGDALOX12 | |
| SCHEMBL7988137 | 0.87 | PRKAB2 (0.52) | DGAT1KCNH2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL7989662 | 0.86 | LMNA (0.45) | DGAT1ALDH1A1HPGDCHEK2KMT2A | |
| SCHEMBL7977723 | 0.86 | SIRT2 (0.48) | LMNAMAPT | |
| SCHEMBL7991773 | 0.85 | PARP1 (0.51) | USP2ALDH1A1CHEK2KMT2ALMNA | |
| SCHEMBL7989957 | 0.85 | USP2 (0.48) | DGAT1USP2ALDH1A1CHEK2KMT2A | |
| SCHEMBL7978156 | 0.84 | AKR1C3 (0.47) | DGAT1ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7989670 | 0.83 | BRD4 (0.41) | DGAT1USP2ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL7977718 | 0.83 | PRKAB2 (0.48) | DGAT1KCNH2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL7991701 | 0.82 | MALT1 (0.41) | DGAT1CHEK2KMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |