Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.51 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.51 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.51 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.51 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.51 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.51 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAP2 | P11137 | 1/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991843 | 0.91 | AURKA (0.45) | PARP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL7991959 | 0.90 | SMN1; SMN2 (0.44) | PARP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL7989662 | 0.89 | LMNA (0.45) | PARP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL7991747 | 0.88 | PARP1 (0.53) | PARP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL7978156 | 0.87 | AKR1C3 (0.47) | PARP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL7988137 | 0.87 | PRKAB2 (0.52) | PARP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL7989957 | 0.85 | USP2 (0.48) | PRKAB2PRKAG1PRKAA2PRKAA1PRKAG3 | |
| SCHEMBL7988555 | 0.85 | PARP1 (0.54) | PARP1SMN1; SMN2PIN1AKR1C3KMT2A | |
| SCHEMBL7991757 | 0.85 | DGAT1 (0.42) | PARP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL7977895 | 0.84 | SIRT2 (0.61) | PARP1MAPTMAP2SIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |