Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.51 |
| ▸ | GCGR | P47871 | 1/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.41 |
| ▸ | CSNK1E | P49674 | 3/20 | 0.41 |
| ▸ | RAF1 | P04049 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988468 | 0.86 | TEK (0.49) | MAPK14MAPK13MAPK12MAPK11ALOX5 | |
| SCHEMBL7977727 | 0.84 | RAF1 (0.55) | MAPK14MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL7991764 | 0.83 | GPR84 (0.38) | MAPK14MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL7995032 | 0.83 | MAPK14 (0.58) | MAPK14MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL7991975 | 0.78 | MAPK14 (0.49) | MAPK14MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL7989739 | 0.77 | MAPK14 (0.56) | MAPK14MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL7995659 | 0.77 | GCGR (0.54) | MAPK14MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL7991767 | 0.77 | MAPK11 (0.57) | MAPK14MAPK13GCGRMAPK12MAPK11 | |
| SCHEMBL7995767 | 0.76 | KDM4E (0.49) | ALDH1A1LMNA | |
| SCHEMBL7989693 | 0.76 | MAPK14 (0.54) | MAPK14MAPK13GCGRMAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |