Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.37 |
| ▸ | GCGR | P47871 | 1/20 | 0.37 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.37 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | PPARA | Q07869 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | TNKS | O95271 | 2/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989665 | 0.87 | GPR84 (0.43) | GPR84GSK3BADKMAPK13GCGR | |
| SCHEMBL7991844 | 0.83 | MAPK14 (0.51) | MAPK13GCGRMAPK12MAPK11MAPK14 | |
| SCHEMBL7995651 | 0.81 | SIRT2 (0.41) | GCGRALOX5SMN1; SMN2TP53MAPT | |
| SCHEMBL7977835 | 0.79 | RAB9A (0.43) | NPC1MAPK1RAB9AL3MBTL1MEN1 | |
| SCHEMBL7992017 | 0.78 | NPBWR1 (0.42) | MAPK13MAPK12MAPK11MAPK14ALDH1A1 | |
| SCHEMBL7989585 | 0.76 | TARBP2 (0.46) | MAPK13GCGRMAPK12MAPK11MAPK14 | |
| SCHEMBL7995767 | 0.75 | KDM4E (0.49) | ALDH1A1LMNASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL7988490 | 0.74 | MAPK14 (0.53) | MAPK13GCGRMAPK12MAPK11MAPK14 | |
| SCHEMBL7977974 | 0.74 | ALOX5 (0.49) | GCGRALDH1A1CYP2C19ALOX5GABRA2 | |
| SCHEMBL7989869 | 0.74 | KDM4E (0.43) | MAPK13GCGRMAPK12MAPK11MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |