Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 9/20 | 0.49 |
| ▸ | GCGR | P47871 | 3/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.49 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.46 |
| ▸ | CDC7 | O00311 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.45 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.44 |
| ▸ | CSNK1E | P49674 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TEK | Q02763 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991767 | 0.89 | MAPK11 (0.57) | MAPK14GCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL7995659 | 0.89 | GCGR (0.54) | MAPK14GCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL7977727 | 0.89 | RAF1 (0.55) | MAPK14GCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL7989693 | 0.88 | MAPK14 (0.54) | MAPK14GCGRMAPK13MAPK12MAPK11 | |
| Hydrochloric Acid SCHEMBL7977803 | 0.88 | GCGR (0.53) | MAPK14GCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL7995167 | 0.85 | MAPK14 (0.54) | MAPK14GCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL7991775 | 0.84 | ALOX5 (0.59) | MAPK14GCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL7977738 | 0.82 | MAPK14 (0.56) | MAPK14GCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL7992039 | 0.82 | MAPK14 (0.56) | MAPK14GCGRMAPK13MAPK12MAPK11 | |
| SCHEMBL7989739 | 0.80 | MAPK14 (0.56) | MAPK14GCGRMAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |