Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.45 |
| ▸ | CD74 | P04233 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.42 |
| ▸ | LPO | P22079 | 2/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.41 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | QPCT | Q16769 | 2/20 | 0.39 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985850 | 0.95 | GAA (0.49) | GAATP53RXFP1ABCG2CD74 | |
| SCHEMBL7974018 | 0.92 | GAA (0.53) | GAATP53RXFP1ABCG2CD74 | |
| SCHEMBL7985653 | 0.91 | GAA (0.46) | GAATP53RXFP1ABCG2CD74 | |
| SCHEMBL7974093 | 0.90 | GAA (0.48) | GAATP53RXFP1ABCG2YTHDC1 | |
| SCHEMBL7974314 | 0.90 | GAA (0.46) | GAATP53RXFP1ABCG2YTHDC1 | |
| SCHEMBL7974584 | 0.90 | GAA (0.56) | GAATP53RXFP1ABCG2YTHDC1 | |
| SCHEMBL7985378 | 0.89 | TSHR (0.47) | GAATP53RXFP1ABCG2YTHDC1 | |
| SCHEMBL7991874 | 0.88 | GAA (0.48) | GAATP53RXFP1ABCG2YTHDC1 | |
| SCHEMBL7985577 | 0.88 | ABCG2 (0.46) | GAATP53RXFP1ABCG2NR1H2 | |
| SCHEMBL7989313 | 0.88 | ROCK2 (0.52) | GAATP53RXFP1YTHDC1LPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |