Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | UBE2N | P61088 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | YTHDC1 | Q96MU7 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974012 | 0.95 | ALDH1A1 (0.41) | SMN1; SMN2GLAHTTUBE2NL3MBTL1 | |
| SCHEMBL7991646 | 0.94 | SMN1; SMN2 (0.43) | SMN1; SMN2GLAHTTUBE2NL3MBTL1 | |
| SCHEMBL7988668 | 0.94 | SMN1; SMN2 (0.44) | SMN1; SMN2GLAHTTUBE2NL3MBTL1 | |
| SCHEMBL7991566 | 0.93 | ACP1 (0.43) | SMN1; SMN2GLAHTTUBE2NL3MBTL1 | |
| SCHEMBL7987310 | 0.92 | YTHDC1 (0.41) | SMN1; SMN2GLAHTTUBE2NL3MBTL1 | |
| SCHEMBL7975240 | 0.92 | ALDH1A1 (0.42) | SMN1; SMN2GLAHTTUBE2NL3MBTL1 | |
| SCHEMBL7985360 | 0.92 | POLB (0.40) | SMN1; SMN2GLAHTTUBE2NL3MBTL1 | |
| SCHEMBL7988781 | 0.90 | MET (0.43) | SMN1; SMN2GLAHTTUBE2NL3MBTL1 | |
| SCHEMBL7974267 | 0.90 | SMN1; SMN2 (0.43) | SMN1; SMN2GLAHTTUBE2NL3MBTL1 | |
| SCHEMBL7991597 | 0.90 | PDE4B (0.39) | SMN1; SMN2GLAHTTUBE2NL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |