Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.46 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.46 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.46 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 5/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.43 |
| ▸ | GCGR | P47871 | 3/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989686 | 0.85 | PARP1 (0.48) | CHEK2PARP1MAPK14MAPK13MAPK12 | |
| SCHEMBL7989925 | 0.83 | MAPK14 (0.62) | BRAFCHEK2MAPK14MAPK13MAPK12 | |
| SCHEMBL7990026 | 0.83 | GCGR (0.44) | CHEK2MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7989973 | 0.83 | GCGR (0.43) | CHEK2GCGRPIN1 | |
| SCHEMBL7991539 | 0.82 | SIRT2 (0.41) | BRAFCHEK2PARP1MAPK14MAPK13 | |
| SCHEMBL7988519 | 0.81 | GCGR (0.43) | CHEK2MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7995390 | 0.80 | MAPK14 (0.48) | CHEK2PARP1MAPK14MAPK13MAPK12 | |
| SCHEMBL7995219 | 0.80 | RHEB (0.48) | CHEK2PARP1MAPK14MAPK13MAPK12 | |
| SCHEMBL7988555 | 0.80 | PARP1 (0.54) | PARP1PIN1MAPK1 | |
| SCHEMBL7977709 | 0.79 | DHODH (0.58) | CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |