Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 4/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 4/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 4/20 | 0.47 |
| ▸ | RAF1 | P04049 | 2/20 | 0.47 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.46 |
| ▸ | PARP1 | P09874 | 2/20 | 0.46 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.44 |
| ▸ | GCGR | P47871 | 2/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | MAP2 | P11137 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991943 | 0.87 | MAPK14 (0.58) | RHEBMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL7989925 | 0.82 | MAPK14 (0.62) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL7991728 | 0.82 | SIRT2 (0.53) | RHEBPARP1GCGRALOX5LMNA | |
| SCHEMBL7991890 | 0.80 | BRAF (0.48) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL7995390 | 0.79 | MAPK14 (0.48) | MAPK14MAPK13MAPK12MAPK11RAF1 | |
| SCHEMBL7977732 | 0.78 | MAPT (0.56) | MAPK14MAPK13MAPK12MAPK11PARP1 | |
| SCHEMBL7991619 | 0.77 | MEN1 (0.50) | MAPTTSHRHTTCYP1A2MAPK1 | |
| SCHEMBL7989686 | 0.76 | PARP1 (0.48) | MAPK14MAPK13MAPK12MAPK11PIN1 | |
| SCHEMBL7991843 | 0.76 | AURKA (0.45) | PARP1CHEK2LMNAMAPTHTT | |
| SCHEMBL7977691 | 0.76 | PRKAB2 (0.46) | CHEK2GCGRMAPTCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |