Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.46 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7992061 | 1.00 | KMT2A (0.47) | KMT2ANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL17420757 | 0.85 | KMT2A (0.56) | KMT2ANPSR1PPARGNCOA2NCOA1 | |
| SCHEMBL7988181 | 0.84 | CES2 (0.53) | MAPTALDH1A1HTTHDAC3HDAC1 | |
| SCHEMBL7991618 | 0.84 | PARP10 (0.50) | KMT2ANPSR1PARP10MAPTSCN2A | |
| SCHEMBL7991620 | 0.84 | PARP10 (0.50) | KMT2ANPSR1PARP10MAPTSCN2A | |
| SCHEMBL7988180 | 0.84 | CES2 (0.53) | MAPTALDH1A1HTTHDAC3HDAC1 | |
| SCHEMBL18017521 | 0.82 | CES2 (0.48) | KMT2ANPSR1MAPTPOLBALDH1A1 | |
| SCHEMBL7991679 | 0.82 | CES2 (0.48) | KMT2ANPSR1MAPTPOLBALDH1A1 | |
| SCHEMBL7991675 | 0.82 | CES2 (0.48) | KMT2ANPSR1MAPTPOLBALDH1A1 | |
| SCHEMBL16613214 | 0.81 | NPC1 (0.49) | PPARGPARP10MAPTALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |