Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991618 | 1.00 | PARP10 (0.50) | PARP10ALDH1A1NPC1PLK1GAA | |
| SCHEMBL7988180 | 0.88 | CES2 (0.53) | ALDH1A1MAPTKDM4E | |
| SCHEMBL7988181 | 0.88 | CES2 (0.53) | ALDH1A1MAPTKDM4E | |
| SCHEMBL18017521 | 0.86 | CES2 (0.48) | ALDH1A1GAAKMT2ANPSR1RAB9A | |
| SCHEMBL7991679 | 0.86 | CES2 (0.48) | ALDH1A1GAAKMT2ANPSR1RAB9A | |
| SCHEMBL7991675 | 0.86 | CES2 (0.48) | ALDH1A1GAAKMT2ANPSR1RAB9A | |
| SCHEMBL16613214 | 0.84 | NPC1 (0.49) | PARP10ALDH1A1NPC1RAB9ALMNA | |
| SCHEMBL7992061 | 0.84 | KMT2A (0.47) | PARP10ALDH1A1KMT2ANPSR1SCN2A | |
| SCHEMBL7992064 | 0.84 | KMT2A (0.47) | PARP10ALDH1A1KMT2ANPSR1SCN2A | |
| SCHEMBL11430643 | 0.84 | PARP10 (0.59) | PARP10ALDH1A1NPC1PLK1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288061-B1 | INTERLEUKIN INHIBITORS; ASTHMA, BRONCHODILATOR AGENTS, ANTIALLERGENS | WELFIDE CORPORATION (JP) | 2001-09-11 | — | — | US | disclosed |