SCHEMBL7992264

SCHEMBL7992264

CCOC(=O)c1ccc(Cl)cc1F

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.51
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA7 P43166 2/20 0.50
CA9 Q16790 2/20 0.50
CA14 Q9ULX7 2/20 0.50
TSHR P16473 1/20 0.50
ALOX15 P16050 1/20 0.49
CYP4F2 P78329 1/20 0.48
CYP4A11 Q02928 1/20 0.48
NPC1 O15118 1/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.46
PKM P14618 1/20 0.46
MAOB P27338 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19971601 0.88 MAPK1 (0.52) MAPK1CA12CA1CA2CA7
SCHEMBL235046 0.84 TSHR (0.60) MAPK1CA12CA1CA2CA7
SCHEMBL16068653 0.84 CYP11B1 (0.48) ALOX15KMT2AMAOB
SCHEMBL367075 0.83 TSHR (0.57) MAPK1CA12CA1CA2CA7
SCHEMBL5248889 0.83 MAPK1 (0.54) MAPK1CA12CA1CA2CA7
SCHEMBL522136 0.83 KMT2A (0.59) MAPK1CA12CA1CA2CA7
SCHEMBL7222675 0.83 TSHR (0.53) MAPK1CA12CA1CA2CA7
SCHEMBL6318986 0.81 MEN1 (0.50) KMT2AKDM4EMAOB
SCHEMBL10487630 0.81 MAPK1 (0.52) MAPK1CA12CA1CA2CA7
SCHEMBL3304119 0.81 CA12 (0.70) MAPK1CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018057219-A1 METHOD OF ALLOCATING INDIVIDUAL OIL OR WATER PRODUCTION CONTRIBUTIONS FROM MULTIPLE COMBINED SOURCES SPECTRUM TRACER SERVICES, LLC (US) 2018-03-29 WO disclosed
US-20180080314-A1 METHOD OF ALLOCATING INDIVIDUAL OIL OR WATER PRODUCTION CONTRIBUTIONS FROM MULTIPLE COMBINED SOURCES SPECTRUM TRACER SERVICES, LLC 2018-03-22 US disclosed
US-6265418-B1 ANTICOAGULANTS UBE INDUSTRIES, LTD. (JP) 2001-07-24 US disclosed
EP-1020467-A1 N-ACYLAMINO ACID AMIDE COMPOUNDS AND INTERMEDIATES FOR PREPARATION THEREOF UBE INDUSTRIES LIMITED (JP) 2000-07-19 EP disclosed