Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | PDE8B | O95263 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 4/20 | 0.34 |
| ▸ | FLT3 | P36888 | 3/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | TYK2 | P29597 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459073 | 0.84 | ACHE (0.39) | ACHESIGMAR1PDE8BMAPTJAK2 | |
| SCHEMBL20245449 | 0.83 | ACHE (0.41) | ACHESIGMAR1PDE8BMAPTL3MBTL1 | |
| SCHEMBL1161159 | 0.81 | ACHE (0.42) | ACHEPDE8BMAPTL3MBTL1KMT2A | |
| SCHEMBL17825123 | 0.79 | ACHE (0.41) | ACHEPDE8BMAPTL3MBTL1KMT2A | |
| SCHEMBL21743170 | 0.79 | GABRA1 (0.50) | ACHEPDE8BMAPTL3MBTL1KMT2A | |
| SCHEMBL27672079 | 0.79 | ACHE (0.44) | ACHEPDE8BMAPTJAK2FLT3 | |
| SCHEMBL1106841 | 0.79 | ACHE (0.41) | ACHEPDE8BMAPTL3MBTL1KMT2A | |
| SCHEMBL21303995 | 0.79 | ACHE (0.41) | ACHEPDE8BMAPTL3MBTL1KMT2A | |
| SCHEMBL12026627 | 0.79 | ACHE (0.44) | ACHESIGMAR1PDE8BMAPTL3MBTL1 | |
| SCHEMBL5212545 | 0.79 | ACHE (0.41) | ACHEPDE8BMAPTL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6297374-B1 | Nitroimino-nitromethylene—azole or-azine heterocyclic compounds, insecticidal compositions containing them, and insecticidal methods of using them | NIHON BAYER AGROCHEM K.K. (JP) | 2001-10-02 | — | — | US | disclosed |
| US-6022967-A | 1-NITRO-2-CARBOXYVINYL- OR 1-NITRO-2-(DIMETHYLAMINO)VINYL-SUBSTITUTED IMIDAZOLIDINES OR TETRAHYDROPYRIMIDINES | NIHON BAYER AGROCHEM K.K. (JP) | 2000-02-08 | — | — | US | disclosed |
| US-5750704-A | INSECTICIDES | NIHON BAYER AGROCHEM K.K. (JP) | 1998-05-12 | — | — | US | disclosed |
| US-5580889-A | Insecticidal nitromethyl or niteoimino-heteromethyl-heterocyclics | NIHON BAYER AGROCHEM K.K. (JP) | 1996-12-03 | — | — | US | disclosed |
| US-5461167-A | 2-chloro-5-chloromethyl thiazole; insecticide | NIHON BAYER AGROCHEM K.K. (JP) | 1995-10-24 | — | — | US | disclosed |
| US-5428032-A | Insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1995-06-27 | — | — | US | disclosed |
| US-5298507-A | Insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1994-03-29 | — | — | US | disclosed |
| US-5204360-A | Insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1993-04-20 | — | — | US | disclosed |
| US-5001138-A | Insecticides | NIHON TOKUSHU NOYAKU SEIZO, K.K. (JP) | 1991-03-19 | — | — | US | disclosed |
| US-4845106-A | INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1989-07-04 | — | — | US | disclosed |
| US-4742060-A | 2-(NITROIMINO)- OR 2-(NITROMETHYLENE)-IMIDAZOLIDINES AS INSECTICIDES | NIHON TOKUSHU NOYAKU SEIZO K. K. (JP) | 1988-05-03 | — | — | US | disclosed |