Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.62 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.62 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.62 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.53 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | IDH1 | O75874 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | ASH1L | Q9NR48 | 4/20 | 0.42 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | HNF4A | P41235 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7896302 | 0.95 | PRSS1 (0.68) | PRSS1PRSS2PRSS3PLA2G2APLA2G10 | |
| SCHEMBL7897904 | 0.89 | PLA2G10 (0.64) | PRSS1PRSS2PRSS3PLA2G2APLA2G10 | |
| SCHEMBL7898203 | 0.80 | MAOA (0.52) | PRSS1PRSS2PRSS3SMN1; SMN2F10 | |
| SCHEMBL8665442 | 0.80 | PRSS1 (0.61) | PRSS1PRSS2PRSS3PLA2G2APLA2G10 | |
| SCHEMBL7900704 | 0.77 | SMN1; SMN2 (0.57) | PLA2G2APLA2G10SMN1; SMN2LMNALOXL2 | |
| SCHEMBL7900761 | 0.77 | IGF1R (0.49) | PRSS1PRSS2PRSS3LMNAF10 | |
| SCHEMBL4224616 | 0.77 | PLA2G2A (0.69) | PRSS1PRSS2PRSS3PLA2G2APLA2G10 | |
| SCHEMBL7889322 | 0.76 | IGF1R (0.47) | PRSS1PRSS2PRSS3LMNA | |
| SCHEMBL7900726 | 0.76 | IGF1R (0.47) | PRSS1PRSS2PRSS3LMNA | |
| SCHEMBL7895911 | 0.75 | LMNA (0.55) | PRSS1PRSS2PRSS3PLA2G2APLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277998-B1 | REACTING 2-CYANO-4-OXO-4H-BENZOPYRAN COMPOUND WITH HYDROGEN SULFIDE AND THEN REACTING PROUDCT WITH ALKYL HALIDE; REACTING THE PRODUCT WITH HYDRAZINE OR ITS SALT AND THEN WITH NITROUS ACID COMPOUND TO OBTAIN TETRAZOLE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-08-21 | — | — | US | disclosed |