SCHEMBL7992968

SCHEMBL7992968

CC(O)c1cccc(OC(C)(C)C(=O)NN)c1

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 9/20 0.43
CNR2 P34972 7/20 0.43
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
AOC3 Q16853 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
OGG1 O15527 1/20 0.39
PTGS1 P23219 1/20 0.38
PFKFB3 Q16875 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12670847 0.80 LMNA (0.47)
SCHEMBL7998547 0.80 CYP3A4 (0.45) CNR1CNR2
SCHEMBL7994910 0.78 CNR1 (0.48) CNR1CNR2KMT2A
SCHEMBL7991799 0.78 OGG1 (0.55) CNR1CNR2MEN1KMT2AOGG1
SCHEMBL6055145 0.77 UGT2B7 (0.44) MEN1KMT2AAOC3L3MBTL1PTGS1
SCHEMBL12670838 0.75 PDK1 (0.44) CNR1CNR2
SCHEMBL30806448 0.72 CETP (0.46)
SCHEMBL29699132 0.72 CETP (0.46)
SCHEMBL1047410 0.72 CETP (0.46)
SCHEMBL14536898 0.72 CETP (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010001946-A1 TRIAZOLE DERIVATIVE OR SALT THEREOF アステラス製薬株式会社 (JP) 2010-01-07 WO disclosed