Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PRKACA | P17612 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7990740 | 0.95 | ROCK2 (0.40) | CDC7ROCK2MAP4K4PIM1PRKACA | |
| SCHEMBL7993164 | 0.89 | ROCK2 (0.42) | CDC7ROCK2MAP4K4PIM1PRKACA | |
| SCHEMBL7978376 | 0.84 | ROCK2 (0.41) | CDC7ROCK2MAP4K4PIM1PRKACA | |
| SCHEMBL7993013 | 0.83 | ROCK2 (0.41) | CDC7ROCK2MAP4K4PIM1PRKACA | |
| SCHEMBL5380552 | 0.81 | XDH (0.53) | CDC7ROCK2MAP4K4PIM1PRKACA | |
| SCHEMBL7989732 | 0.76 | GAA (0.52) | CDC7ROCK2MAP4K4PIM1PRKACA | |
| SCHEMBL7989847 | 0.76 | CDC7 (0.43) | CDC7ROCK2MAP4K4PIM1PRKACA | |
| SCHEMBL7993806 | 0.72 | FABP1 (0.45) | CDC7ROCK2MAP4K4PIM1PRKACA | |
| SCHEMBL7993027 | 0.72 | CA1 (0.40) | CDC7ROCK2MAP4K4PIM1PRKACA | |
| SCHEMBL10840691 | 0.71 | CDC7 (0.44) | CDC7ROCK2PRKACACDK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001070727-A1 | 2-(ARYLALKYLAMINO)PYRIMIDONE DERIVATIVES AND 2-(HETEROARYLALKYLAMINO)PYRIMIDONE DERIVATIVES | SANOFI-SYNTHELABO (FR) | 2001-09-27 | — | — | WO | disclosed |