Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | CDC7 | O00311 | 4/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.47 |
| ▸ | GSK3B | P49841 | 3/20 | 0.47 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.47 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989847 | 0.87 | CDC7 (0.43) | XDHRECQLFABP4CDC7ROCK2 | |
| SCHEMBL7993806 | 0.85 | FABP1 (0.45) | XDHRECQLFABP4CDC7ROCK2 | |
| SCHEMBL7996305 | 0.83 | CDC7 (0.45) | CDC7KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL7991079 | 0.83 | ALOX5 (0.41) | XDHRECQLFABP4CDC7ROCK2 | |
| SCHEMBL7992999 | 0.81 | CDC7 (0.40) | XDHFABP4CDC7ROCK2GSK3B | |
| SCHEMBL7993164 | 0.80 | ROCK2 (0.42) | CDC7ROCK2GSK3BMAP4K4CLK4 | |
| SCHEMBL5375269 | 0.80 | CDC7 (0.43) | CDC7GSK3BCDK2HPGDLMNA | |
| SCHEMBL7989732 | 0.80 | GAA (0.52) | CDC7ROCK2GSK3BMAP4K4CLK4 | |
| SCHEMBL7990975 | 0.80 | HSD17B10 (0.49) | CDC7ROCK2CLK4MEN1ALDH1A1 | |
| SCHEMBL7990740 | 0.80 | ROCK2 (0.40) | XDHFABP4CDC7ROCK2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7256199-B1 | Pyrimidone derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-14 | — | — | US | claimed |
| US-7256199-B1 | Pyrimidone derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |
| EP-1115721-B1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEM CORP (JP) | 2003-12-10 | — | — | EP | disclosed |
| EP-1115721-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018758-A1 | PYRIMIDONE DERIVATIVES | MITSUBISHI CHEMICAL CORPORATION (JP) | 2000-04-06 | — | — | WO | disclosed |