SCHEMBL7993035

SCHEMBL7993035

C[C](Cc1ccccc1)c1ccccc1Br

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.49
LMNA P02545 1/20 0.47
KMT2A Q03164 3/20 0.42
KDM4E B2RXH2 1/20 0.42
NLRP3 Q96P20 1/20 0.41
SMN1; SMN2 Q16637 3/20 0.40
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
AKR1B1 P15121 1/20 0.40
GAA P10253 1/20 0.40
MEN1 O00255 2/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
SIGMAR1 Q99720 1/20 0.39
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
ALDH1A1 P00352 1/20 0.39
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9099802 0.78 SMN1; SMN2 (0.57) HPGDKMT2ASMN1; SMN2CES2CES1
SCHEMBL5971439 0.76 HPGD (0.49) HPGDLMNAKMT2AKDM4ENLRP3
SCHEMBL3132603 0.76 HPGD (0.53) HPGDLMNAKMT2AKDM4ENLRP3
SCHEMBL1824047 0.74 SMN1; SMN2 (0.50) HPGDLMNAKMT2ASMN1; SMN2AKR1B1
SCHEMBL9133864 0.74 GABRA1 (0.42) HPGDLMNASMN1; SMN2CES2CES1
SCHEMBL758421 0.73 KDM4E (0.50) HPGDLMNAKMT2AKDM4EMEN1
SCHEMBL9877760 0.73 CES2 (0.57) HPGDLMNAKMT2AKDM4ENLRP3
SCHEMBL153922 0.72 CES1 (0.48) LMNAKMT2ACES2CES1AKR1B1
SCHEMBL5172196 0.71 ALDH1A1 (0.43) HPGDKMT2ASMN1; SMN2GAAMEN1
SCHEMBL66721 0.68 CES1 (0.55) KMT2ACES2CES1AKR1B1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6140389-A SPRAYING AN INK COMPRISING AT LEAST RESIN PARTICLES DISPERSED IN A NONAQUEOUS CARRIER LIQUID HAVING A SPECIFIC ELECTRIC RESISTANCE AND DIELECTRIC CONSTANT ON A PLATE TO FORM AN IMAGE; DESENSITIZING A NONIMAGE AREA OF BINDER AND ZINC OXIDE FUJI PHOTO FILM CO., LTD. (JP) 2000-10-31 US disclosed