Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28911779 | 0.87 | POLB (0.47) | POLBMEN1KMT2ACA1CA2 | |
| SCHEMBL6866079 | 0.84 | MEN1 (0.44) | POLBMEN1KMT2ACA1CA2 | |
| SCHEMBL6867510 | 0.82 | FAAH (0.46) | POLBMEN1KMT2ACA1CA2 | |
| SCHEMBL8863095 | 0.82 | POLB (0.43) | POLBMEN1KMT2ACA1CA2 | |
| SCHEMBL888672 | 0.77 | MEN1 (0.50) | POLBMEN1KMT2ACA1CA2 | |
| SCHEMBL8112639 | 0.77 | — | — | |
| SCHEMBL8829446 | 0.77 | FAAH (0.53) | POLBMEN1KMT2ACA1CA2 | |
| SCHEMBL6273408 | 0.75 | MEN1 (0.55) | POLBMEN1KMT2AFAAHMGLL | |
| SCHEMBL5385733 | 0.74 | POLB (0.66) | POLBMEN1KMT2ACHRM2CHRM4 | |
| SCHEMBL1982535 | 0.74 | MGLL (0.52) | POLBMEN1KMT2AFAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109897059-B | Synthetic method of lithium battery auxiliary agent 3-cyanopropyl dimethyl fluorosilane | 山东东岳有机硅材料股份有限公司 | 2021-05-18 | — | — | CN | claimed |
| CN-109897059-B | Synthetic method of lithium battery auxiliary agent 3-cyanopropyl dimethyl fluorosilane | 山东东岳有机硅材料股份有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-109897059-B | Synthetic method of lithium battery auxiliary agent 3-cyanopropyl dimethyl fluorosilane | 山东东岳有机硅材料股份有限公司 | 2021-05-18 | — | — | CN | disclosed |
| US-20200216465-A1 | DIARYL MACROCYCLES AS MODULATORS OF PROTEIN KINASES | TURNING POINT THERAPEUTICS INC (US) | 2020-07-09 | — | — | US | disclosed |
| EP-3636650-A1 | DIARYL MACROCYCLES AS MODULATORS OF PROTEIN KINASES | Turning Point Therapeutics, Inc. (US) | 2020-04-15 | — | — | EP | disclosed |
| EP-3636649-A1 | DIARYL MACROCYCLES AS MODULATORS OF PROTEIN KINASES | Turning Point Therapeutics, Inc. (US) | 2020-04-15 | — | — | EP | disclosed |
| US-10618912-B2 | Diaryl macrocycles as modulators of protein kinases | Turning Point Therapeutics, Inc. (US) | 2020-04-14 | — | — | US | disclosed |
| US-20190169207-A1 | DIARYL MACROCYCLES AS MODULATORS OF PROTEIN KINASES | Turning Point Therapeutics, Inc. | 2019-06-06 | — | — | US | disclosed |
| EP-3097107-B1 | DIARYL MACROCYCLES AS MODULATORS OF PROTEIN KINASES | TP THERAPEUTICS INC (US) | 2019-04-17 | — | — | EP | disclosed |
| US-10246466-B2 | Diaryl macrocycles as modulators of protein kinases | TP THERAPEUTICS, INC. (US) | 2019-04-02 | — | — | US | disclosed |
| US-5977248-A | POLYSILOXANES | DOW CORNING CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| US-5977248-A | POLYSILOXANES | DOW CORNING CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
| US-5888397-A | CHROMATOGRAPHY; CONTAINING POLYOXYETHYLENE GLYCOL | ARCH DEVELOP. CORP. (US) | 1999-03-30 | — | — | US | disclosed |
| EP-0830189-A1 | RECOVERING CHAOTROPIC ANIONS FROM AQUEOUS SOLUTION | ARCH DEVELOPMENT CORPORATION (US) | 1998-03-25 | — | — | EP | disclosed |
| US-5707525-A | Process for separating and recovering an anionic dye from an aqueous solution | ARCH DEVELOPMENT CORP. (US) | 1998-01-13 | — | — | US | disclosed |
| US-5603834-A | CONTACTING SEPARATION PARTICLES WITH AQUEOUS SOLUTION CONTAINING PERTECHNETATE IONS AND POLYETHYLENE GLYCOL LIQUID/LIQUID BIPHASE FORMING AMOUNT OF DISSOLVED SALT TO BIND IONS, FREEING, RECOVERING | ARCH DEVELOPMENT CORP. (US) | 1997-02-18 | — | — | US | disclosed |
| WO-1996040396-A1 | RECOVERING CHAOTROPIC ANIONS FROM AQUEOUS SOLUTION | ARCH DEVELOPMENT CORPORATION (US) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996040397-A1 | SEPARATING ANIONIC DYE FROM AQUEOUS SOLUTION | ARCH DEVELOPMENT CORPORATION (US) | 1996-12-19 | — | — | WO | disclosed |
| US-4456551-A | Azo dyes from 2-amino-5-alkylthio-1,3,4-thiadiazoles and N-acyloxyalkyl-m-acylamidoanilines | EASTMAN KODAK COMPANY (US) | 1984-06-26 | — | — | US | disclosed |
| US-4395368-A | RED POLYESTER DYE | EASTMAN KODAK COMPANY (US) | 1983-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190169207-A1 | DIARYL MACROCYCLES AS MODULATORS OF PROTEIN KINASES | MAP3K20, LCK, DAPK2 | POLB 3299/4885MEN1 2963/4885KMT2A 1565/4885 |
| US-10618912-B2 | Diaryl macrocycles as modulators of protein kinases | MAP3K20, LCK, MAP3K1 | POLB 3670/4885MEN1 2490/4885KMT2A 1557/4885 |
| US-20200216465-A1 | DIARYL MACROCYCLES AS MODULATORS OF PROTEIN KINASES | MAP3K20, LCK, MAP3K1 | POLB 3670/4885MEN1 2490/4885KMT2A 1557/4885 |
| US-10246466-B2 | Diaryl macrocycles as modulators of protein kinases | MAP3K20, LCK, MAP3K1 | POLB 3670/4885MEN1 2490/4885KMT2A 1557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.