Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.49 |
| ▸ | CCR1 | P32246 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1712491 | 0.79 | MTNR1A (0.41) | RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7117048 | 0.76 | PARP1 (0.47) | RAB9APARP1CYP1A2MEN1KMT2A | |
| SCHEMBL25312907 | 0.75 | METAP2 (0.47) | METAP2CCR1RAB9ACCR5PARP1 | |
| SCHEMBL2115749 | 0.69 | CCR1 (0.64) | METAP2CCR1RAB9ACCR5PARP1 | |
| SCHEMBL806441 | 0.69 | CCR1 (0.64) | METAP2CCR1RAB9ACCR5PARP1 | |
| 8-Hydroxy Quinaldine SCHEMBL1715251 | 0.68 | METAP2 (0.57) | METAP2CCR1RAB9ACCR5PARP1 | |
| 8-Hydroxy Quinaldine SCHEMBL2059590 | 0.68 | METAP2 (0.57) | METAP2CCR1RAB9ACCR5PARP1 | |
| 8-Hydroxy Quinaldine SCHEMBL1714719 | 0.68 | METAP2 (0.57) | METAP2CCR1RAB9ACCR5PARP1 | |
| SCHEMBL13991767 | 0.68 | CCR1 (0.48) | METAP2CCR1KMT2AALDH1A1TSHR | |
| 8-Hydroxy Quinaldine SCHEMBL4399934 | 0.68 | METAP2 (0.57) | METAP2CCR1RAB9ACCR5PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000015617-A1 | 2-AMINOETHYL-QUINOLINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE | SANOFI-SYNTHELABO (FR) | 2000-03-23 | — | — | WO | disclosed |