SCHEMBL25312907

SCHEMBL25312907

Cc1ccc2cccc(C3CCCCC3)c2n1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 1/20 0.47
CCR1 P32246 1/20 0.45
RAB9A P51151 1/20 0.45
CCR5 P51681 1/20 0.45
PDK2 Q15119 2/20 0.42
PDK4 Q16654 2/20 0.42
PARP1 P09874 1/20 0.41
GLO1 Q04760 2/20 0.40
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
MCHR1 Q99705 3/20 0.38
POLB P06746 1/20 0.36
CASP3 P42574 1/20 0.36
SENP7 Q9BQF6 1/20 0.36
SENP6 Q9GZR1 1/20 0.36
AGTR1 P30556 1/20 0.36
PAX8 Q06710 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5884609 0.80 MCHR1 (0.57) MCHR1
SCHEMBL22288175 0.76 ALDH1A1 (0.49) METAP2CCR1CCR5PDK2PARP1
SCHEMBL7993066 0.75 METAP2 (0.49) METAP2CCR1RAB9ACCR5PARP1
SCHEMBL13740154 0.72 CCR1 (0.48) METAP2CCR1RAB9ACCR5PDK2
SCHEMBL31240954 0.72 HTR2C (0.52)
SCHEMBL31173132 0.71 LRRK2 (0.38) RAB9APDK2PDK4KDM4EPOLB
SCHEMBL13739471 0.70 CCR1 (0.45) METAP2CCR1RAB9ACCR5PDK2
SCHEMBL8056158 0.69 DRD2 (0.50) CCR1KDM4EALDH1A1LMNAHPGD
SCHEMBL8181776 0.69 CCR1 (0.48) METAP2CCR1RAB9ACCR5PDK2
SCHEMBL7648672 0.69 CYP2A6 (0.47) RAB9AKDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134776-A1 IRON-CATALYZED HIGHLY ENANTIOSELECTIVE CIS-DIHYDROXYLATION OF QUINONES VERSITECH LIMITED (CN) 2023-07-20 WO disclosed