Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 5/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7995324 | 0.71 | HTT (0.55) | HTTSLC6A2SLC6A3LMNACYP1A2 | |
| SCHEMBL7995089 | 0.70 | HTT (0.54) | HTTSLC6A2SLC6A3LMNACYP1A2 | |
| SCHEMBL7998683 | 0.69 | HTT (0.53) | HTTSLC6A2SLC6A3LMNACYP1A2 | |
| SCHEMBL2975670 | 0.68 | HTT (0.47) | HTTSLC6A2SLC6A3LMNACYP1A2 | |
| SCHEMBL10693246 | 0.68 | HTT (0.51) | HTTSLC6A2SLC6A3LMNACYP1A2 | |
| SCHEMBL2491022 | 0.68 | HTT (0.41) | HTTSLC6A2SLC6A3LMNACYP1A2 | |
| SCHEMBL23070558 | 0.67 | HTT (0.40) | HTTSLC6A2SLC6A3LMNACYP1A2 | |
| SCHEMBL12180835 | 0.67 | HTT (0.40) | HTTSLC6A2SLC6A3LMNACYP1A2 | |
| SCHEMBL14305067 | 0.66 | HTT (0.49) | HTTSLC6A2SLC6A3LMNACYP1A2 | |
| SCHEMBL10351845 | 0.64 | HTT (0.47) | HTTSLC6A2SLC6A3LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009129-A2 | 1H-PIRIDO[3, 4-B]INDOL-1-ONE DERIVATIVES | NOVUSPHARMA S.P.A. (IT) | 2001-02-08 | — | — | WO | disclosed |