Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998689 | 0.79 | HTT (0.48) | HTTL3MBTL1MAPTTDP1MAPK1 | |
| SCHEMBL7995089 | 0.79 | HTT (0.54) | HTTL3MBTL1MAPTTDP1MAPK1 | |
| SCHEMBL7998683 | 0.78 | HTT (0.53) | HTTLTB4RCYP2C19LMNACYP1A2 | |
| SCHEMBL17921822 | 0.74 | LTA4H (0.39) | HTTTDP1LMNASLC6A2SLC6A3 | |
| SCHEMBL7998680 | 0.73 | HTT (0.48) | HTTPOLBSMN1; SMN2LTA4HMAPK14 | |
| SCHEMBL7992008 | 0.72 | HTT (0.47) | HTTL3MBTL1MAPTLMNAMAOB | |
| SCHEMBL7993157 | 0.71 | HTT (0.49) | HTTL3MBTL1MAPTTDP1MAPK1 | |
| SCHEMBL7524246 | 0.71 | HTT (1.00) | HTTL3MBTL1POLBCYP2C19LMNA | |
| SCHEMBL7995327 | 0.71 | HTT (0.46) | HTTTDP1MAPK1POLBLMNA | |
| SCHEMBL7981094 | 0.70 | HTT (0.45) | HTTL3MBTL1MAPTTDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001009129-A2 | 1H-PIRIDO[3, 4-B]INDOL-1-ONE DERIVATIVES | NOVUSPHARMA S.P.A. (IT) | 2001-02-08 | — | — | WO | disclosed |