SCHEMBL7993226

SCHEMBL7993226

CC(C)(C)C(C(=O)O)[C@H](N)[C]=O

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
MAPT P10636 1/20 0.43
PTGS1 P23219 1/20 0.43
SLC7A5 Q01650 1/20 0.37
SLC1A3 P43003 1/20 0.30
SLC1A2 P43004 1/20 0.30
SLC1A1 P43005 1/20 0.30
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1604917 0.74 ALDH1A1 (0.39) ALDH1A1MAPTPTGS1SLC7A5
SCHEMBL7917712 0.74 ALDH1A1 (0.36) ALDH1A1MAPTPTGS1SLC7A5
SCHEMBL7919870 0.74 ALDH1A1 (0.36) ALDH1A1MAPTPTGS1SLC7A5
SCHEMBL8966152 0.73 SLC7A5 (0.48) ALDH1A1MAPTPTGS1SLC7A5SLC1A3
SCHEMBL318356 0.73 SLC7A5 (0.48) ALDH1A1MAPTPTGS1SLC7A5SLC1A3
SCHEMBL6974551 0.73 SLC7A5 (0.48) ALDH1A1MAPTPTGS1SLC7A5SLC1A3
SCHEMBL3891579 0.73 SLC7A5 (0.55) ALDH1A1MAPTPTGS1SLC7A5SLC1A3
SCHEMBL4441664 0.73 SLC7A5 (0.55) ALDH1A1MAPTPTGS1SLC7A5SLC1A3
Methane SCHEMBL2033946 0.71 SLC7A5 (0.52) ALDH1A1MAPTPTGS1SLC7A5SLC1A3
Methane SCHEMBL2032537 0.71 SLC7A5 (0.52) ALDH1A1MAPTPTGS1SLC7A5SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001021599-A1 CASPASE INHIBITOR LG CHEMICAL LTD. (KR) 2001-03-29 WO disclosed
US-4956504-A IMMUNOMODULATORS, ANTIBIOTICS ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1990-09-11 US disclosed
EP-0309971-A2 New spergualin-related compound and pharmaceutical composition ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1989-04-05 EP disclosed
EP-0241797-A2 Novel spergualin-related compounds and process for producing the same MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 1987-10-21 EP disclosed