Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPL | P40238 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | CHEK2 | O96017 | 7/20 | 0.57 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.55 |
| ▸ | MMP8 | P22894 | 1/20 | 0.55 |
| ▸ | MMP13 | P45452 | 1/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993472 | 0.90 | MPL (0.71) | MPLALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL3567770 | 0.89 | CHEK2 (0.66) | MPLALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL3569187 | 0.89 | CHEK2 (0.66) | MPLALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL3925655 | 0.86 | CHEK2 (0.68) | MPLHDAC3HDAC1HDAC8HDAC6 | |
| SCHEMBL3917925 | 0.86 | CHEK2 (0.68) | MPLALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL5189120 | 0.85 | CHEK2 (0.69) | MPLALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL7602620 | 0.84 | KDM4E (0.70) | MPLALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL11599478 | 0.84 | KDM4E (0.70) | MPLALDH1A1KDM4EKMT2AHPGD | |
| SCHEMBL15788683 | 0.83 | NPC1 (0.57) | ALDH1A1KDM4EKMT2AHPGDHDAC3 | |
| SCHEMBL28930292 | 0.83 | KDM4E (0.68) | ALDH1A1KDM4EKMT2AHPGDHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010024833-A1 | Methods for the solid phase synthesis of combinatorial libraries of benzimidazol, benzoxazoles, benzothiazoles, and derivatives thereof | LABORDE EDGARDO (US) | 2001-09-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010024833-A1 | Methods for the solid phase synthesis of combinatorial libraries of benzimidazol, benzoxazoles, benzothiazoles, and derivatives thereof | EIF2AK2, CDK15, CDK17 | MPL 2107/4885ALDH1A1 3805/4885KDM4E 2008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.