Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.37 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993615 | 1.00 | KDM4E (0.46) | KDM4EMAPTMEN1KMT2ACYP2D6 | |
| SCHEMBL8190644 | 0.82 | CYP1A2 (0.44) | KDM4EMAPTMEN1KMT2ACYP2D6 | |
| SCHEMBL8190647 | 0.82 | CYP1A2 (0.44) | KDM4EMAPTMEN1KMT2ACYP2D6 | |
| Hydrochloric Acid SCHEMBL9068728 | 0.81 | LMNA (0.44) | KDM4EMAPTMEN1KMT2ACYP2D6 | |
| SCHEMBL8184028 | 0.78 | ALDH1A1 (0.47) | KDM4EMAPTMEN1KMT2ACYP2D6 | |
| SCHEMBL8184031 | 0.78 | ALDH1A1 (0.47) | KDM4EMAPTMEN1KMT2ACYP2D6 | |
| SCHEMBL8005822 | 0.76 | CYP1A1 (0.52) | KDM4EMAPTMEN1KMT2ACYP2D6 | |
| SCHEMBL8005817 | 0.76 | CYP1A1 (0.52) | KDM4EMAPTMEN1KMT2ACYP2D6 | |
| SCHEMBL8191019 | 0.76 | CYP1A2 (0.46) | MAPTMEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL8191021 | 0.76 | CYP1A2 (0.46) | MAPTMEN1KMT2ACYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000020005-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING AN OPIATE ANALGESIC AND A SYNERGIZING SUBSTANCE | EGIS Gyógyszergyár Rt. (HU) | 2000-04-13 | — | — | WO | claimed |
| WO-2000020005-A1 | PHARMACEUTICAL COMPOSITIONS CONTAINING AN OPIATE ANALGESIC AND A SYNERGIZING SUBSTANCE | EGIS Gyógyszergyár Rt. (HU) | 2000-04-13 | — | — | WO | disclosed |