Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8190647 | 1.00 | CYP1A2 (0.44) | CYP1A2CYP1A1CYP1B1MAPTKMT2A | |
| Hydrochloric Acid SCHEMBL9068728 | 0.99 | LMNA (0.44) | CYP1A2CYP1A1CYP1B1MAPTKMT2A | |
| SCHEMBL8184028 | 0.83 | ALDH1A1 (0.47) | CYP1A2CYP1A1CYP1B1MAPTKMT2A | |
| SCHEMBL8184031 | 0.83 | ALDH1A1 (0.47) | CYP1A2CYP1A1CYP1B1MAPTKMT2A | |
| SCHEMBL8191021 | 0.82 | CYP1A2 (0.46) | CYP1A2CYP1A1CYP1B1MAPTKMT2A | |
| SCHEMBL8191019 | 0.82 | CYP1A2 (0.46) | CYP1A2CYP1A1CYP1B1MAPTKMT2A | |
| SCHEMBL7993615 | 0.82 | KDM4E (0.46) | CYP1A2CYP1A1CYP1B1MAPTKMT2A | |
| SCHEMBL7993617 | 0.82 | KDM4E (0.46) | CYP1A2CYP1A1CYP1B1MAPTKMT2A | |
| SCHEMBL8345585 | 0.79 | MEN1 (0.47) | CYP1A2MAPTKMT2ACYP2D6MEN1 | |
| SCHEMBL8345582 | 0.79 | MEN1 (0.47) | CYP1A2MAPTKMT2ACYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6075018-A | TRANQUILIZERS | EGIS GYOGYSZERGYAR RT. (HU) | 2000-06-13 | — | — | US | disclosed |