Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27617788 | 0.82 | MTNR1A (0.58) | ALDH1A1F2F10RAB9A | |
| SCHEMBL27535182 | 0.82 | ESR1 (0.52) | ESR1ESR2ALDH1A1MAPTCXCR1 | |
| SCHEMBL7259084 | 0.80 | ESR1 (0.50) | ESR1ESR2ALDH1A1 | |
| SCHEMBL25832024 | 0.80 | ACACB (0.44) | ALDH1A1CXCR1CXCR2PKML3MBTL1 | |
| SCHEMBL29174147 | 0.78 | MAPT (0.46) | ALDH1A1MAPTHTTPKML3MBTL1 | |
| SCHEMBL4856212 | 0.77 | ACACB (0.42) | ALDH1A1CXCR1CXCR2PKML3MBTL1 | |
| SCHEMBL10642651 | 0.77 | ALDH1A1 (0.43) | ALDH1A1MAPTHTTL3MBTL1ATM | |
| SCHEMBL17875268 | 0.76 | ACHE (0.61) | ALDH1A1MAPTHTTL3MBTL1RAB9A | |
| SCHEMBL28827835 | 0.76 | MAPT (0.47) | ALDH1A1MAPTHTTL3MBTL1RAB9A | |
| SCHEMBL16442234 | 0.75 | KMT2A (0.47) | ALDH1A1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277984-B1 | USE AS FLUORESCENT MARKERS; FOR IMPARTING FLUORESCENCE TO BIOLOGICAL AND NONBIOLOGICAL MATERIALS TODETECT VARIOUS BIOLOGICAL OR OTHER MATERIALS BY PROCEDURES SUCH AS FLUORESCENCE MICROSCOPY | CARNEGIE MELLON UNIVERSITY | 2001-08-21 | — | — | US | disclosed |