SCHEMBL7993980

SCHEMBL7993980

COC(=O)c1ccc2c(c1C)SCC2O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 1/20 0.39
ALDH1A1 P00352 4/20 0.35
PDK2 Q15119 2/20 0.35
PDK4 Q16654 2/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA9 Q16790 1/20 0.35
CA14 Q9ULX7 1/20 0.35
MAPT P10636 2/20 0.35
TSHR P16473 2/20 0.35
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
MAPK10 P53779 1/20 0.35
KMT2A Q03164 1/20 0.35
PTK2B Q14289 1/20 0.35
NCOA1 Q15788 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30574254 1.00 PTGER4 (0.39) PTGER4ALDH1A1PDK2PDK4CA12
SCHEMBL5956528 0.86 PTGER4 (0.40) PTGER4ALDH1A1PDK2PDK4CA12
SCHEMBL5956888 0.86 PTGER4 (0.40) PTGER4ALDH1A1PDK2PDK4CA12
SCHEMBL7980017 0.84 PTGER4 (0.39) PTGER4ALDH1A1PDK2PDK4CA12
SCHEMBL5956884 0.76 PTGER4 (0.42) PTGER4ALDH1A1PDK2PDK4CA12
SCHEMBL5956737 0.76 PTGER4 (0.42) PTGER4ALDH1A1PDK2PDK4CA12
SCHEMBL7994474 0.72 PTGER4 (0.39) PTGER4ALDH1A1PDK2PDK4TSHR
SCHEMBL10164852 0.72 PTGER4 (0.43) PTGER4ALDH1A1PDK2PDK4CA12
SCHEMBL7620950 0.71 ALDH1A1 (0.40) PTGER4ALDH1A1PDK2PDK4CA12
SCHEMBL3422644 0.71 CA12 (0.54) PTGER4ALDH1A1PDK2PDK4CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116602296-B Weeding composition containing propyzamide 成武县晨晖环保科技有限公司 2023-09-15 CN disclosed
CN-116602296-A Weeding composition containing propyzamide 成武县晨晖环保科技有限公司 2023-08-18 CN disclosed
CN-104768937-B The aryl bicyclic carboxylic acid amide of activity of weeding 拜尔农作物科学股份公司 2016-11-23 CN disclosed
US-20150216171-A1 HERBICIDALLY ACTIVE BICYCLOARYL CARBOXYLIC ACID AMIDES BAYER CROPSCIENCE AG (DE) 2015-08-06 US disclosed
CN-104768937-A Herbicidally active bicycloaryl carboxylic acid amides BAYER CROPSCIENCE AG 2015-07-08 CN disclosed
US-6291682-B1 FOR CONTROLLING WEEDS BASF AKTIENGESELLSCHAFT (DE) 2001-09-18 US disclosed
US-6054414-A HERBICIDE BASF AKTIENGESELLSCHAFT (DE) 2000-04-25 US disclosed
CN-1194644-A Pyrazol-4-yl-benzoyl derivatives and their use as herbicides BASF AG (DE) 1998-09-30 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150216171-A1 HERBICIDALLY ACTIVE BICYCLOARYL CARBOXYLIC ACID AMIDES AADAC, DDT, AOX1 PTGER4 2907/4885ALDH1A1 554/4885PDK2 422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.