Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HTR5A | P47898 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5956888 | 1.00 | PTGER4 (0.40) | PTGER4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL30574254 | 0.86 | PTGER4 (0.39) | PTGER4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7993980 | 0.86 | PTGER4 (0.39) | PTGER4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5956737 | 0.85 | PTGER4 (0.42) | PTGER4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL5956884 | 0.85 | PTGER4 (0.42) | PTGER4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7323896 | 0.84 | DRD2 (0.43) | MEN1KMT2AALDH1A1KDM4EDRD2 | |
| SCHEMBL27504228 | 0.84 | TSHR (0.33) | PTGER4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7994474 | 0.81 | PTGER4 (0.39) | PTGER4MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL7809913 | 0.78 | KDM4E (0.33) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL5956763 | 0.77 | MEN1 (0.40) | PTGER4MEN1KMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1730049-A1 | COSMETIC PORTION | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-12-13 | — | — | EP | disclosed |
| EP-1270570-B1 | AMIDE COMPOUNDS AND USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005085089-A1 | COSMETIC PORTION | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2005-09-15 | — | — | WO | disclosed |
| US-6933305-B2 | Amide compounds and use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2005-08-23 | — | — | US | disclosed |
| US-20030158413-A1 | Amide compounds and use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2003-08-21 | — | — | US | disclosed |
| EP-1270570-A1 | AMIDE COMPOUNDS AND USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6291682-B1 | FOR CONTROLLING WEEDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-18 | — | — | US | disclosed |
| US-6054414-A | HERBICIDE | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158413-A1 | Amide compounds and use thereof | ROCK2, ROCK1, RHOT2 | PTGER4 2079/4885MEN1 2543/4885KMT2A 1253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.