Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | IAPP | P10997 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SHBG | P04278 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31317052 | 1.00 | TRPA1 (0.50) | TRPA1ATMHSPA5MAPTHSD17B10 | |
| SCHEMBL6914998 | 0.83 | TSHR (0.38) | TRPA1ATMMAPTHSD17B10TP53 | |
| SCHEMBL3655349 | 0.82 | TRPA1 (0.63) | TRPA1ATMHSPA5MAPTHSD17B10 | |
| SCHEMBL845508 | 0.81 | HSPA5 (0.56) | TRPA1ATMHSPA5MAPTHSD17B10 | |
| SCHEMBL286623 | 0.79 | PDCD1 (0.55) | TRPA1ATMHSPA5MAPTHSD17B10 | |
| SCHEMBL2021799 | 0.79 | GABRA1 (0.58) | TRPA1ATMHSPA5MAPTHSD17B10 | |
| SCHEMBL30970850 | 0.79 | GABRA1 (0.58) | TRPA1ATMHSPA5MAPTHSD17B10 | |
| SCHEMBL10665469 | 0.77 | TRPA1 (0.50) | TRPA1ATMHSPA5MAPTHSD17B10 | |
| SCHEMBL5398644 | 0.77 | TRPA1 (0.50) | TRPA1ATMHSPA5MAPTHSD17B10 | |
| SCHEMBL8900885 | 0.77 | TRPA1 (0.50) | TRPA1ATMHSPA5MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103209679-B | Cosmetic and topical skin preparation comprising higher alcohol-modified silicone | 道康宁东丽株式会社 | 2017-08-11 | — | — | CN | disclosed |
| CN-102946852-B | Comprise the powder-processed agent of the organopolysiloxane of sugar alcohol modification | DOW CORNING TORAY CO.,LTD. (JP) | 2016-03-16 | — | — | CN | disclosed |
| CN-103209679-A | Cosmetic and topical skin preparation comprising higher alcohol-modified silicone | DOW CORNING TORAY CO LTD | 2013-07-17 | — | — | CN | disclosed |
| CN-102946852-A | Powder treatment agent comprising sugar alcohol -modified organopolysiloxane | DOW CORNING TORAY CO LTD | 2013-02-27 | — | — | CN | disclosed |
| CN-101227889-B | Cosmetics comprising a modified organopolysiloxane | DOW CORNING TORAY CO LTD | 2012-11-07 | — | — | CN | disclosed |
| CN-102666663-A | Novel organopolysiloxane copolymer | DOW CORNING TORAY CO LTD | 2012-09-12 | — | — | CN | disclosed |
| CN-101316578-A | Silicone vesicles containing actives | DOW CORNING (US) | 2008-12-03 | — | — | CN | disclosed |
| CN-101227889-A | Cosmetics comprising a modified organopolysiloxane | DOW CORNING TORAY CO LTD (JP) | 2008-07-23 | — | — | CN | disclosed |
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |