SCHEMBL286623

SCHEMBL286623

Cc1c(O)cccc1CO

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 2/20 0.55
CD274 Q9NZQ7 2/20 0.55
TRPA1 O75762 2/20 0.52
ATM Q13315 1/20 0.52
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
MAPT P10636 4/20 0.42
TP53 P04637 2/20 0.42
TSHR P16473 2/20 0.42
LMNA P02545 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ALOX12 P18054 1/20 0.42
HSPA5 P11021 1/20 0.42
HSD17B10 Q99714 2/20 0.42
GAA P10253 1/20 0.42
MAPK1 P28482 1/20 0.42
GABRA1 P14867 1/20 0.41
GABRB2 P47870 1/20 0.41
IAPP P10997 1/20 0.38
CYP2D6 P10635 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL8207395 0.94 PDCD1 (0.50) PDCD1CD274TRPA1ATMMEN1
SCHEMBL6424004 0.85 PDCD1 (0.64) PDCD1CD274TRPA1ATMMEN1
SCHEMBL845508 0.83 HSPA5 (0.56) TRPA1ATMMAPTTP53TSHR
SCHEMBL1917838 0.82 TRPA1 (0.48) PDCD1CD274TRPA1ATMMEN1
SCHEMBL2021799 0.81 GABRA1 (0.58) TRPA1ATMMAPTTP53HSPA5
SCHEMBL30970850 0.81 GABRA1 (0.58) TRPA1ATMMAPTTP53HSPA5
SCHEMBL7994002 0.79 TRPA1 (0.50) TRPA1ATMMAPTTP53TSHR
SCHEMBL31317052 0.79 TRPA1 (0.50) TRPA1ATMMAPTTP53TSHR
SCHEMBL5398644 0.79 TRPA1 (0.50) TRPA1ATMMAPTTP53TSHR
SCHEMBL10665469 0.79 TRPA1 (0.50) TRPA1ATMMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 164 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025095046-A1 RESIN COMPOSITION, DRY FILM, CURED PRODUCT, AND LIGHT EMITTING ELEMENT MOUNTED SUBSTRATE 太陽ホールディングス株式会社 2025-05-08 WO disclosed
WO-2025095045-A1 TRANSPARENT RESIN COMPOSITION, DRY FILM, CURED PRODUCT, AND ELECTRONIC COMPONENT 太陽ホールディングス株式会社 2025-05-08 WO disclosed
EP-3083573-B1 INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL MERCK SHARP & DOHME LLC (US) 2024-08-07 EP disclosed
WO-2024009612-A1 CURABLE RESIN, AND METHODS FOR MANUFACTURING CURABLE RESIN INTERMEDIATE, CURABLE RESIN, CURABLE RESIN COMPOSITION, AND CURED PRODUCT 株式会社日本触媒 2024-01-11 WO disclosed
CN-112225681-B Preparation method of 2, 4-di (n-octylthiomethylene) -6-methylphenol 江苏极易新材料有限公司 2021-06-01 CN disclosed
EP-3255993-B1 INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL MERCK SHARP & DOHME (US) 2021-01-27 EP disclosed
CN-112225681-A Preparation method of 2, 4-di (n-octylthiomethylene) -6-methylphenol 江苏极易新材料有限公司 2021-01-15 CN disclosed
EP-3169672-B1 INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL MERCK SHARP & DOHME (US) 2020-04-29 EP disclosed
CN-110537147-A Photosensitive polymer combination NISSAN CHEMICAL IND LTD 2019-12-03 CN disclosed
CN-110537146-A Photosensitive resin composition NISSAN CHEMICAL CORP 2019-12-03 CN disclosed
WO-2005111003-A1 AMINO-TETRAZOLES ANALOGUES AND METHODS OF USE ABBOTT LABORATORIES (US) 2005-11-24 WO disclosed
CN-1167670-C Aryl carboxylic acid and tetrazole derivant - 2004-09-22 CN disclosed
EP-1013639-B1 Aryl carboxylic acid and tetrazole derivatives comprising a carbamoyloxy unit HOFFMANN LA ROCHE (CH) 2003-10-01 EP disclosed
US-6335459-B1 PROSTAGLANDIN I2 RECEPTOR MODULATORS; TREATING TISSUE NECROSIS, PREMATURE UTERINE CONTRACTION, GASTRIC ULCERATION, SEXUAL DYSFUNCTION, MENSTRUAL PAIN AND IMPROPER WOUND HEALING, IMMUNOREGULATION, PLATELET AGGREGATION OR NEUTROPHIL FUNCTION SYNTEX (U.S.A.) LLC 2002-01-01 US disclosed
WO-2001034573-A1 COMPOUNDS ASTRAZENECA AB (SE) 2001-05-17 WO disclosed
WO-2001034578-A1 COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY ASTRAZENECA AB (SE) 2001-05-17 WO disclosed
US-6141987-A Absorption refrigerating system and working mixture for said system GAZ DE FRANCE (FR) 2000-11-07 US disclosed
CN-1266054-A Aryl carboxylic acid and tetrazole derivant HOFFMANN LA ROCHE (CH) 2000-09-13 CN disclosed
EP-1013639-A1 Aryl carboxylic acid and tetrazole derivatives comprising a carbamoyloxy unit F. HOFFMANN-LA ROCHE AG (CH) 2000-06-28 EP disclosed
EP-0386639-A1 Process for preparing para-hydroxybenzyl alcohol MITSUBISHI PETROCHEMICAL CO., LTD. (JP) 1990-09-12 EP disclosed