Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | RBBP9 | O75884 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7369196 | 0.80 | ALDH1A1 (0.45) | ALDH1A1PLA2G4ASMN1; SMN2L3MBTL1PKM | |
| SCHEMBL8800422 | 0.79 | ALDH1A1 (0.43) | ALDH1A1PLA2G4ACES1RBBP9TBXAS1 | |
| SCHEMBL7378370 | 0.74 | ALDH1A1 (0.39) | ALDH1A1PLA2G4AL3MBTL1PKMCCNB2 | |
| SCHEMBL28027936 | 0.74 | — | — | |
| SCHEMBL5848285 | 0.72 | HDAC3 (0.38) | ALDH1A1PLA2G4ASMN1; SMN2PKMCES1 | |
| SCHEMBL16922260 | 0.72 | — | — | |
| SCHEMBL3504222 | 0.72 | — | — | |
| Bromide SCHEMBL6329679 | 0.71 | PLA2G4A (0.56) | ALDH1A1PLA2G4ASMN1; SMN2L3MBTL1PKM | |
| SCHEMBL28219561 | 0.69 | ALDH1A1 (0.68) | ALDH1A1PLA2G4ASMN1; SMN2L3MBTL1CES1 | |
| SCHEMBL4438959 | 0.69 | POLB (0.54) | ALDH1A1SMN1; SMN2HTTLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001087852-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL URACILS USEFUL FOR SELECTIVE INHIBITION OF THE COAGULATION CASCADE | PHARMACIA CORPORATION (US) | 2001-11-22 | — | — | WO | claimed |