SCHEMBL7994342

SCHEMBL7994342

O=C(O)c1cccc(C(=O)c2cc(Cl)cc(C(=O)c3ccccc3O)c2O)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.52
HPGD P15428 4/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
KDM4E B2RXH2 2/20 0.52
CA12 O43570 1/20 0.52
HMGB1 P09429 1/20 0.52
CA4 P22748 1/20 0.52
CA6 P23280 1/20 0.52
CA7 P43166 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
CA9 Q16790 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
CA14 Q9ULX7 1/20 0.52
HNF4A P41235 1/20 0.51
GSTA1 P08263 2/20 0.47
CYP3A4 P08684 2/20 0.47
CYP2C9 P11712 1/20 0.47
KMT2A Q03164 1/20 0.47
AKR1C4 P17516 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7798423 0.88 ALDH1A1 (0.65) ALDH1A1HPGDCA1CA2KDM4E
SCHEMBL22938973 0.81 ALDH1A1 (0.65) ALDH1A1HPGDCA1CA2KDM4E
SCHEMBL9686287 0.79 SELL (0.66) ALDH1A1HPGDCA1CA2KDM4E
SCHEMBL21812546 0.78 AKR1C2 (0.68) ALDH1A1HPGDKDM4EHNF4ACYP3A4
SCHEMBL5962842 0.76 GSTA1 (0.62) ALDH1A1HPGDCA1CA2KDM4E
SCHEMBL9450719 0.76 CA1 (0.70) ALDH1A1HPGDCA1CA2KDM4E
SCHEMBL30740067 0.75 LIG1 (0.55) ALDH1A1HPGDCA1CA2KDM4E
SCHEMBL1334176 0.75 ALDH1A1 (0.74) ALDH1A1HPGDCA1CA2KDM4E
SCHEMBL301928 0.75 LIG1 (0.55) ALDH1A1HPGDCA1CA2KDM4E
Salicylic Acid SCHEMBL28162812 0.75 ALDH1A1 (0.67) ALDH1A1HPGDCA1CA2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6288265-B1 HYDROXYBENZOIC ACID OR HYDROXYBENZAMIDE DERIVATIVES NATIONAL SCIENCE COUNCIL (TW) 2001-09-11 US disclosed
US-6121255-A 7-(PHLOROGLUCIDAMIDO)CEPHALOSPORINS OR CEPHALOSPORIN 3'-PHLOROGLUCIDE ESTER ANTIBIOTICS NATIONAL SCIENCE COUNCIL (TW) 2000-09-19 US disclosed