Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5761752 | 0.78 | SMN1; SMN2 (0.42) | OPRK1HTT | |
| SCHEMBL3911930 | 0.68 | HSD17B10 (0.48) | MGLLPTGDR2 | |
| SCHEMBL5201104 | 0.67 | EPHX1 (0.40) | L3MBTL1 | |
| SCHEMBL17814806 | 0.67 | FOLH1 (0.55) | FOLH1OPRK1L3MBTL1TGM2HTT | |
| SCHEMBL5760993 | 0.67 | PNMT (0.45) | L3MBTL1 | |
| SCHEMBL1889179 | 0.66 | HTT (0.62) | FOLH1L3MBTL1TGM2HTT | |
| SCHEMBL26293783 | 0.65 | MGLL (0.45) | MGLLPTGDR2 | |
| SCHEMBL23082858 | 0.64 | ACP3 (0.51) | L3MBTL1MGLL | |
| SCHEMBL5206641 | 0.64 | PNMT (0.50) | OPRK1L3MBTL1 | |
| SCHEMBL13168003 | 0.64 | KCNQ3 (0.49) | MGLLTGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291457-B1 | SUBSTITUTED IMIDAZOLE COMPOUNDS | MERCK & CO., INC. | 2001-09-18 | — | — | US | disclosed |