Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8863111 | 0.89 | NPSR1 (0.55) | MAPTALDH1A1NPSR1LMNASMN1; SMN2 | |
| SCHEMBL7994381 | 0.88 | NPSR1 (0.46) | MAPTTAS1R3TAS1R1ALDH1A1KDM4E | |
| SCHEMBL7876429 | 0.81 | NPSR1 (0.57) | MAPTMAPK1TSHRTAS1R3TAS1R1 | |
| SCHEMBL825343 | 0.78 | SMN1; SMN2 (0.49) | MAPTMAPK1ALDH1A1KDM4ENPC1 | |
| SCHEMBL7867528 | 0.78 | KMT2A (0.62) | MAPTMAPK1TSHRTAS1R3TAS1R1 | |
| SCHEMBL7867554 | 0.78 | TAS1R3 (0.56) | MAPTMAPK1TSHRTAS1R3TAS1R1 | |
| Hydrochloric Acid SCHEMBL21494472 | 0.77 | PDE4A (0.52) | MAPTMAPK1TSHRALDH1A1KDM4E | |
| SCHEMBL3558885 | 0.76 | PDE4A (0.60) | MAPTMAPK1NPSR1LMNASMN1; SMN2 | |
| SCHEMBL30568367 | 0.76 | PDE4A (0.60) | MAPTMAPK1NPSR1LMNASMN1; SMN2 | |
| SCHEMBL21494483 | 0.76 | PDE4A (0.60) | MAPTMAPK1NPSR1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284780-B1 | PREVENT TUMOR NECROSIS FACTOR RETROVIRUS REPRODUCTION | CELGENE CORPORATION | 2001-09-04 | — | — | US | disclosed |