Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 3/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.44 |
| ▸ | F7 | P08709 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994479 | 0.89 | MAPT (0.46) | NPSR1SMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL7994381 | 0.88 | NPSR1 (0.46) | NPSR1SMN1; SMN2MAPTLMNAKMT2A | |
| SCHEMBL825343 | 0.87 | SMN1; SMN2 (0.49) | NPSR1SMN1; SMN2MAPTLMNAPOLB | |
| SCHEMBL7994728 | 0.81 | ALDH1A1 (0.40) | SMN1; SMN2MAPTLMNAKMT2AMEN1 | |
| SCHEMBL6693234 | 0.80 | PDE4A (0.50) | NPSR1SMN1; SMN2LMNAKMT2APOLB | |
| SCHEMBL7876133 | 0.79 | NPSR1 (0.71) | NPSR1SMN1; SMN2MAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL21494472 | 0.79 | PDE4A (0.52) | NPSR1SMN1; SMN2MAPTLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL28323446 | 0.79 | PDE4A (0.49) | NPSR1SMN1; SMN2LMNAKMT2APOLB | |
| SCHEMBL27827515 | 0.78 | ALDH1A1 (0.47) | SMN1; SMN2LMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL2997281 | 0.77 | TNF (0.58) | NPSR1SMN1; SMN2MAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800505-A1 | NOVEL IMMUNOTHERAPEUTIC ARYL AMIDES | CELGENE CORPORATION (US) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996020915-A1 | NOVEL IMMUNOTHERAPEUTIC ARYL AMIDES | CELGENE CORPORATION (US) | 1996-07-11 | — | — | WO | disclosed |