Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7994479 | 0.88 | MAPT (0.46) | NPSR1MAPTLMNASMN1; SMN2TAS1R3 | |
| SCHEMBL8863111 | 0.88 | NPSR1 (0.55) | NPSR1MAPTLMNASMN1; SMN2PDE4A | |
| SCHEMBL7867583 | 0.83 | NPSR1 (0.58) | NPSR1MAPTLMNASMN1; SMN2TAS1R3 | |
| SCHEMBL7874393 | 0.80 | NPSR1 (0.57) | NPSR1MAPTLMNASMN1; SMN2TAS1R3 | |
| SCHEMBL7867322 | 0.80 | KMT2A (0.63) | NPSR1MAPTLMNASMN1; SMN2TAS1R3 | |
| SCHEMBL825343 | 0.78 | SMN1; SMN2 (0.49) | NPSR1MAPTLMNASMN1; SMN2PDE4A | |
| SCHEMBL7874397 | 0.76 | ALDH1A1 (0.56) | NPSR1MAPTLMNASMN1; SMN2TAS1R3 | |
| SCHEMBL16496178 | 0.76 | ROCK2 (0.47) | MAPTLMNAKMT2AGAA | |
| Hydrochloric Acid SCHEMBL21494472 | 0.75 | PDE4A (0.52) | NPSR1MAPTLMNASMN1; SMN2PDE4A | |
| SCHEMBL21494483 | 0.74 | PDE4A (0.60) | NPSR1MAPTLMNASMN1; SMN2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284780-B1 | PREVENT TUMOR NECROSIS FACTOR RETROVIRUS REPRODUCTION | CELGENE CORPORATION | 2001-09-04 | — | — | US | disclosed |
| EP-0800505-A1 | NOVEL IMMUNOTHERAPEUTIC ARYL AMIDES | CELGENE CORPORATION (US) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996020915-A1 | NOVEL IMMUNOTHERAPEUTIC ARYL AMIDES | CELGENE CORPORATION (US) | 1996-07-11 | — | — | WO | disclosed |